Lupus is a severe auto-immune disease where the body’s defense mechanisms, instead of providing it normal defensive function, create antibodies that damage healthy tissues and internal organs.
Under regular function, the immunity mechanism makes proteins known as antibodies, as a way to protect and deal with antigens such as bacteria and viruses. Lupus makes the defense system unable to distinguish between antigens and nutritious tissues. This turns the defense system to lead antibodies against the nutritious tissues – not only antigens – resulting in swelling, soreness, and tissue deterioration.
For many individuals, lupus may be a minor disease affecting only one or two body organs; but for some others, it may result in severe and possibly life-threatening complications.
Types of Lupus
There are many types of lupus disease that are identified these days. These are:
This ailment affects the skin, triggering thick, red, scaly breakouts on the neck, face and scalp. Once the rashes disappear, it can leave scars and can result in thinning hair in the scalp section. The rashes of discoid lupus may continue for some days or several years. It can disappear for some time and then come again. Discoid lupus is considerably more common in females than males and normally occurs between the age groups of 20 to 45.
Systemic Lupus Erythematosus
Also known as SLE, is the disease type that many people indicate when they speak about something severe. It was assigned its name by a nineteenth century French physician who believed that the facial allergy of many people with lupus, appeared like the scratch or bite of a wolf. It is the most severe type of lupus. SLE can threaten the skin, joint parts, and muscles. It may also threaten organs such as the brain, heart, respiratory system, and renal system. The signs of systemic lupus may be severe or mild and often appear and disappear as time passes. Typical symptoms include:
- Distressing joints
- Rashes brought on by exposure to the sun
- Hair loss
- Deprivation of blood circulation in feet or fingers
- Bloating in the thighs
- Peptic issues inside the oral cavity
- Swollen glands
- Overwhelming fatigue
It is brought on by a response to particular sorts of medicines. For instance, some anti-seizure medications and acne drugs can trigger this kind of illness in teenagers. Drug-induced lupus is identical to SLE in the means it affects the human body, but once an individual stops taking the drugs, the symptoms normally disappears.
This type is also incredibly uncommon. It arises when a mother who have certain types of antibodies, transfers them to her baby during the time of birth. Indications in the baby can include rashes, anemia, and very rarely, heart disease that can result in the death of the baby. In the majority of situations, neonatal lupus doesn’t need to be remedied and goes away within a couple of weeks.
The causes of lupus are not identified. Research indicates that genes play a vital role, but genes alone usually do not verify who gets lupus. It is possible that a lot of factors result in the disease. In other words, there isn’t any definite identification of exact lupus causes. However, there are numerous approaches are currently working for the condition and an extensive research for causes of lupus and lupus on the whole.
The majority of experts agree that inherited genes or inheritance is definitely one factor in identifying an individual’s propensity for getting lupus. To determine if you fall in this group, take a look at your family’s health background. Keep in mind, though, a genealogy or family history does not mean that a person will get lupus, the only thing is that he/she is more at risk. It is also necessary to realize that, at present, there is no medical proof that inherited genes plays an important role, however scientists believe that it is possible.
Another path where experts are looking is an ecological factor as a lupus cause. These environmental factors might involve exposure to UV light (photosensitivity), cigarettes, stress, and exposure to harmful toxins for example, trichloroethylene in water and silica particles. It has been proven that some medicines are suspected causes of flares and lupus. In fact, a part of the ailment, drug-stimulated lupus is dependent on this perception. This sort of lupus is generally the result of long-term use of specific medicines (covered more exclusively in different types of lupus).
Scientific studies implies that hormonal issues are associated with autoimmune ailment, though scientific studies are still working and the association between both of them is still unclear.